MUC2 CysD2 domain - ISB Datasets

Unit / Facility

Swedish NMR Centre (Gothenburg) + MPE core

System / Target

Second CysD domain (CysD2) from intestinal mucin MUC2; NMR solution structure, SAXS and MS/MST to understand mucin network organisation and cross-linking.

Organism / Source

Human MUC2 domain

Approx. Data Collection Years

~2021–2024

Access / Reuse Status

Public

Main Public Repository / Storage

PDB + SASBDB + journal SI (+ proteomics repository)

Techniques Used

SAXS NMR MS / Proteomics Biophysics (ITC/SPR/MST/DSF etc.) Integrative / computational modelling (non-MD)

Repository Links

PDB: 8S03
SASBDB: SASDSG5
Publication: Cell Reports 43:114207 (2024)
SciLifeLab Publication: SciLifeLab Publication
MS dataset: ID (likely PRIDE) to be added from paper

Publications

MUC2 CysD2 domain structure and mucin network organisation Cell Reports (2024) DOI: 10.1016/j.celrep.2024.114207 PubMed: 38733585

Machine-Readable Metadata

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