{
  "id": "ISB-D-0035",
  "portal_index": 35,
  "title": "Pyridine-fused 2-pyridones – amyloid fibril binding",
  "portal_description": "Pyridine-fused 2-pyridones as amyloid fibril binding agents; cryo-EM and NMR.",
  "portal_landing_page_url": "https://wpotrzebowski.github.io/isb_datasets/datasets/dataset-36.html",
  "unit_facility": "Cryo-EM / Swedish NMR Centre",
  "system_target": "Amyloid fibril binding by pyridine-fused 2-pyridones",
  "organism_source": "Amyloid fibrils (synthetic compounds)",
  "approx_data_collection_years": "~2018",
  "access": {"status": "public", "license": null, "license_url": null},
  "main_public_repository_storage": "Publication (J. Org. Chem.)",
  "techniques": [
    {"code": "cryo_em", "label": "Cryo-EM"},
    {"code": "nmr", "label": "NMR"},
    {"code": "integrative_modelling", "label": "Integrative / computational modelling (non-MD)"}
  ],
  "repository_records": [
    {"kind": "Publication", "accession": "10.1021/acs.joc.8b03015", "url": "https://doi.org/10.1021/acs.joc.8b03015", "relation": "primary_publication"}
  ],
  "publications": [
    {"type": "journal_article", "title": "Pyridine-fused 2-pyridones – amyloid fibril binding", "venue": "J. Org. Chem. (2018)", "doi": "10.1021/acs.joc.8b03015", "url": "https://doi.org/10.1021/acs.joc.8b03015", "relation": "primary_publication"}
  ],
  "keywords": ["amyloid", "2-pyridones", "cryo-EM", "NMR"]
}