{"id":"ISB-D-0014","portal_index":14,"title":"Streptolysin O accelerates plasminogen to plasmin","portal_description":"Streptolysin O accelerates the conversion of plasminogen to plasmin; structural proteomics and kinetics combined with MS quantification.","portal_landing_page_url":"https://wpotrzebowski.github.io/isb_datasets/datasets/dataset-15.html","unit_facility":"Clinical Proteomics and Immunology / Malmström Lab (Lund)","system_target":"Streptolysin O accelerates the conversion of plasminogen to plasmin.","organism_source":"Streptococcus pyogenes (Streptolysin O) / Human plasminogen","approx_data_collection_years":"~2022–2024","access":{"status":"public","license":null,"license_url":null},"main_public_repository_storage":"PDB; Nat Commun (2024); PRIDE if deposited","techniques":[{"code":"ms_proteomics","label":"MS / Proteomics"},{"code":"biophysics","label":"Biophysics (ITC/SPR/MST/DSF etc.)"},{"code":"integrative_modelling","label":"Integrative / computational modelling (non-MD)"}],"repository_records":[{"kind":"Publication","doi":"10.1038/s41467-024-54173-6","url":"https://doi.org/10.1038/s41467-024-54173-6","relation":"primary_publication"}],"publications":[{"type":"journal_article","title":"Streptolysin O accelerates the conversion of plasminogen to plasmin","venue":"Nat Commun (2024)","doi":"10.1038/s41467-024-54173-6","url":"https://doi.org/10.1038/s41467-024-54173-6","relation":"primary_publication"}],"keywords":["Streptolysin O","plasminogen","S. pyogenes","proteomics"]}